CD276 Protein (CD276) (His tag)
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北京 101111
Quick Overview for CD276 Protein (CD276) (His tag) (ABIN7194787)
抗原
See all CD276 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD276 protein is labelled with His tag.
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原理
- Recombinant Human B7-H3/CD276 Protein (His Tag)
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序列
- Met 1-Thr 461
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产品特性
- A DNA sequence encoding the human CD276 (Q5ZPR3-1) extracellular domain (Met 1-Thr 461) was expressed, with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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CD276 (CD276) (AA 29-245) protein (His tag,mFc Tag)
CD276 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD276 (CD276) (AA 27-461) (Active) protein (hFc Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-245) (Active) protein (Biotin,His-Avi Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-245) (Active) protein (His tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 29-244) protein (Fc Tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD276 (CD276) (AA 29-248) (Active) protein (His tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD276 (CD276) (AA 28-238) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant ELISA, PI, SDS, WB
CD276 (CD276) (AA 28-140) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant ELISA, PI, SDS, WB
CD276 (CD276) (AA 237-461) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant ELISA, PI, SDS, WB
CD276 (CD276) (AA 29-245) protein (Fc Tag,AVI tag,Biotin)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD276
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别名
- B7-H3/CD276
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背景
- B7 homolog 3,B7-H3,B7H34Ig-B7-H3,CD276,CD276 antigen,CD276 Molecule,Costimulatory molecule,B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.
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分子量
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Calculated MW: 48.0 kDa
Observed MW: 73 kDa
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基因ID
- 80381
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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