Quick Overview for CD276 Protein (CD276) (Fc Tag) (ABIN7320967)
抗原
See all CD276 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD276 protein is labelled with Fc Tag.
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原理
- Recombinant Cynomolgus B7-H3/CD276 Protein (Fc Tag)
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序列
- Leu29-Glu465
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产品特性
- Recombinant Cynomolgus CD276 Molecule is produced by our Mammalian expression system and the target gene encoding Leu29-Glu465 is expressed with a Fc tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD276 (CD276) (AA 29-245) protein (Fc Tag)
CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-245) protein (His tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD276 (CD276) (AA 27-461) protein (Fc Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-465) protein (His tag)CD276 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-245) protein (His-Avi Tag,Biotin)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-245) protein (mFc-His Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD276 (CD276) (AA 29-248) protein (His tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-244) protein (Fc Tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD276 (CD276) (AA 28-140) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 237-461) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD276
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别名
- B7-H3/CD276
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背景
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Background: CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20-27 % amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
Synonym: CD276 antigen, CD276, B7 homolog 3, B7-H3,CD276
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分子量
- 74 kDa
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NCBI登录号
- XP_015308534
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途径
- Cancer Immune Checkpoints
抗原
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