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CD27 Protein (Fc-His Tag)

This Recombinant CD27 protein is expressed in HEK-293 Cells.
产品编号 ABIN7318277
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD27 Protein (Fc-His Tag) (ABIN7318277)

抗原

See all CD27 蛋白
CD27 (CD27 Molecule (CD27))

蛋白类型

Recombinant

宿主

  • 25
  • 14
  • 5
  • 4
人

资源

  • 20
  • 9
  • 6
  • 5
  • 2
  • 2
  • 1
HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This CD27 protein is labelled with Fc-His Tag.

    原理

    Recombinant Human CD27/TNFRSF7 Protein (Fc & His Tag)

    序列

    Thr 21-Ile192

    产品特性

    Recombinant Human CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a Fc, 6His tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27/TNFRSF7

    背景

    S152,S152. LPFS2,S152.LPFS2,T14,TNFRSF7,Tp55,CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.

    分子量

    Calculated MW: 47.2 kDa

    Observed MW: 60 kDa

    基因ID

    939

    UniProt

    P26842

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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