CD226 Protein (CD226) (AA 19-247) (Fc Tag)
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Quick Overview for CD226 Protein (CD226) (AA 19-247) (Fc Tag) (ABIN7319664)
抗原
See all CD226 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-247
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标记
- This CD226 protein is labelled with Fc Tag.
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原理
- Recombinant Human CD226/DNAM-1 Protein (Fc Tag)
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序列
- Glu19-Asn247
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产品特性
- Recombinant Human CD226 Antigen is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a Fc tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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CD226 (CD226) (AA 19-247) (Active) protein (His-Avi Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) (Active) protein (Biotin,His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD226 (CD226) (AA 19-247) protein (His tag,mFc Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) (AA 19-254) protein (Fc Tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
CD226 (CD226) proteinCD226 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
CD226 (CD226) (AA 19-254) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD226 (CD226) (AA 1-265) (Active) protein (Fc Tag)CD226 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. ELISA Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD226
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别名
- CD226/DNAM-1
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背景
- CD226,CD226 antigen,DNAM-1,DNAM1,DNAX accessory molecule 1,Human DNAX accessory molecule 1 (DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain (ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation, it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung.
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分子量
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Calculated MW: 52.8 kDa
Observed MW: 72-90 kDa
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基因ID
- 10666
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UniProt
- Q15762
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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