CD160 Protein (CD160) (His tag)
Quick Overview for CD160 Protein (CD160) (His tag) (ABIN7320849)
抗原
See all CD160 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD160 protein is labelled with His tag.
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原理
- Recombinant Mouse CD160/BY55 Protein (His Tag)
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序列
- Gly28-Ser160
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产品特性
- Recombinant Mouse CD160 is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD160
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别名
- CD160/BY55
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背景
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Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
Synonym: CD160 Antigen, Natural Killer Cell Receptor BY55, CD160, BY55
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分子量
- 15.8 kDa
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UniProt
- Q8VC80
抗原
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