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CD160 Protein (CD160) (AA 1-158) (Fc Tag)

This Recombinant CD160 protein is expressed in HEK-293 Cells.
产品编号 ABIN7321007
发货至: 中国
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Quick Overview for CD160 Protein (CD160) (AA 1-158) (Fc Tag) (ABIN7321007)

抗原

See all CD160 蛋白
CD160

蛋白类型

Recombinant

宿主

  • 18
  • 8
  • 2
  • 1
猕猴

资源

  • 10
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HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-158

    标记

    This CD160 protein is labelled with Fc Tag.

    原理

    Recombinant Rhesus macaque CD160 Protein (Fc Tag)

    序列

    Met1-Leu158

    产品特性

    Recombinant Rhesus macaque CD160 is produced by our Mammalian expression system and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD160

    别名

    CD160

    背景

    CD160,CD160 antigen,CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+)peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen,peripheral blood,and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

    分子量

    Calculated MW: 45 kDa

    Observed MW: 55-65 kDa

    UniProt

    G7MG20
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