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CD14 Protein (CD14) (His tag)

CD14 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7194701
发货至: 中国
  • 抗原 See all CD14 蛋白
    CD14
    蛋白类型
    Recombinant
    宿主
    • 22
    • 5
    • 3
    • 1
    • 1
    • 1
    大鼠
    资源
    • 15
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD14 protein is labelled with His tag.
    原理
    Recombinant Rat CD14 Protein (His Tag)
    序列
    Met1-Tyr341
    产品特性
    A DNA sequence encoding the rat Cd14 (Q63691) (Met1-Tyr341) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg protein as determined by the LAL method.
    Top Product
    Discover our top product CD14 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule Protein, CD14 antigen Protein, CD14 Protein, Cd14 Protein
    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

    Synonym: CD14

    分子量
    36.7 kDa
    UniProt
    Q63691
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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