Cathepsin D Protein (CTSD) (His tag)
Quick Overview for Cathepsin D Protein (CTSD) (His tag) (ABIN7318253)
抗原
See all Cathepsin D (CTSD) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cathepsin D protein is labelled with His tag.
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原理
- Recombinant Human Cathepsin D/CTSD Protein (His Tag)
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序列
- Leu21-Leu412
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产品特性
- Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin D (CTSD) (AA 26-412) protein (GST tag)
CTSD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin D (CTSD) (AA 21-410) (Active) protein (His tag)CTSD 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Cathepsin D (CTSD) protein (His tag)CTSD 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cathepsin D (CTSD) (AA 67-403), (partial) protein (GST tag)CTSD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Cathepsin D (CTSD)
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别名
- Cathepsin D/CTSD
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背景
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Background: The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8 % ) compared with non-demented controls (4.9 %). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family
Synonym: Cathepsin D, CTSD,CLN10,CPSD,HEL-S-130P
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分子量
- 43.8 kDa
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UniProt
- P07339
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途径
- Peptide Hormone Metabolism
抗原
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