CPE Protein (His tag)
Quick Overview for CPE Protein (His tag) (ABIN7318246)
抗原
See all CPE 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CPE protein is labelled with His tag.
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原理
- Recombinant Human Carboxypeptidase E/CPE Protein (His Tag)
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序列
- Arg42-Ser453
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产品特性
- Recombinant Human Carboxypeptidase E is produced by our Mammalian expression system and the target gene encoding Arg42-Ser453 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Carboxypeptidase E (CPE) (AA 43-476) protein (His tag)
CPE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Carboxypeptidase E (CPE) proteinCPE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM ZnCl2,10 % Glycerol, pH 7.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CPE (Carboxypeptidase E (CPE))
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别名
- Carboxypeptidase E/CPE
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背景
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Background: The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
Synonym: Carboxypeptidase E(CPE for short), Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase
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分子量
- 47.1 kDa
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UniProt
- P16870
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途径
- Peptide Hormone Metabolism, Synaptic Membrane
抗原
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