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BDNF 蛋白

This Recombinant BDNF protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7319738
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BDNF 蛋白 (ABIN7319738)

抗原

See all BDNF 蛋白
BDNF (Brain-Derived Neurotrophic Factor (BDNF))

蛋白类型

Recombinant

生物活性

Active

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人, 大鼠, 小鼠

资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human/Mouse/Rat BDNF Protein (Active)

    序列

    His129-Arg247

    产品特性

    Recombinant Human/Mouse/Rat BDNF is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Human BDNF at 2ug/mll(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human BDNF is 2.82 ug/ml .
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    BDNF (Brain-Derived Neurotrophic Factor (BDNF))

    别名

    BDNF

    背景

    Background: Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson',s and Alzheimer',s disease.

    Synonym: Brain-Derived Neurotrophic Factor, BDNF, Abrineurin

    分子量

    13 kDa

    UniProt

    P23560

    途径

    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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