BDNF Protein (AA 19-247)
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北京 101111
Quick Overview for BDNF Protein (AA 19-247) (ABIN7319494)
抗原
See all BDNF 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-247
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原理
- Recombinant Human BDNF Protein (with pro peptide)
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序列
- Ala19-Arg247(R125A,R127A,R128A)
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产品特性
- Recombinant Human BDNF is produced by our E.coli expression system and the target gene encoding Ala19-Arg247 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Brain-Derived Neurotrophic Factor (BDNF) (Active) protein (Biotin)
BDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant WB, CC, in vivo, Diff, CyTox, AD, FM, IF, LCI Active
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-255) protein (GST tag)BDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) protein (GST tag)BDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) proteinBDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Brain-Derived Neurotrophic Factor (BDNF) (AA 137-237), (partial) protein (GST tag)BDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 10 % Trehalose, 100 mM NaCl, 0.02 % Tween 80, pH 6.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- BDNF
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背景
- Abrineurin,BDNF,Brain-Derived Neurotrophic Factor,The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner. Pro-BDNF plays important role in negative regulation of neurotrophic actions in the brain.
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分子量
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Calculated MW: 25.6 kDa
Observed MW: 28 kDa
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基因ID
- 627
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UniProt
- P23560
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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