BCL2L1 Protein (His tag)
Quick Overview for BCL2L1 Protein (His tag) (ABIN7319690)
抗原
See all BCL2L1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This BCL2L1 protein is labelled with His tag.
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原理
- Recombinant Human BCL2L1/Bcl-XL Protein (His Tag)
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序列
- Met1-Arg212
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产品特性
- Recombinant Human BCL2L1 is produced by our E.coli expression system and the target gene encoding Met1-Arg212 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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想要此Protein的其他选项吗?
!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 136,947.45 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 50 mM KCl, 20 % Glycerol, pH 7.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- BCL2L1/Bcl-XL
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背景
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Background: Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.
Synonym: Bcl-2-Like Protein 1, Bcl2-L-1, Apoptosis Regulator Bcl-X, Bcl-X,bcl-xL,BCL-XL/S,bcl-xS,BCL2L,BCLX,BCLXL,BCLXS,PPP1R52
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分子量
- 24.85 kDa
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UniProt
- Q07817
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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