CD147 蛋白
Quick Overview for CD147 蛋白 (ABIN7317976)
抗原
See all CD147 (BSG) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human CD147/Basigin Protein
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序列
- Met 1-His 205
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产品特性
- The mature form of human CD147 (NP_940991.1) extracellular domain (Met 1-His 205) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Basigin (Ok Blood Group) (BSG) (AA 22-205) protein (His tag)
BSG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Basigin (Ok Blood Group) (BSG) (AA 22-207) protein (His-DYKDDDDK-Strep II Tag)BSG 宿主: 人 宿主: HEK-293T Cells Recombinant ELISA, SDS, WB, PI
Basigin (Ok Blood Group) (BSG) (AA 22-205) protein (His tag,AVI tag,Biotin)BSG 宿主: 人 宿主: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Basigin (Ok Blood Group) (BSG) protein (mFc Tag)BSG 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Basigin (Ok Blood Group) (BSG) (AA 22-325) protein (His tag)BSG 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE
Basigin (Ok Blood Group) (BSG) (AA 1-269) protein (GST tag)BSG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Basigin (Ok Blood Group) (BSG) (AA 22-207) protein (hIgG-His-tag)BSG 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Basigin (Ok Blood Group) (BSG) (Active) protein (His tag,Fc Tag)BSG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Basigin (Ok Blood Group) (BSG) (AA 1-209) protein (His tag)BSG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Basigin (Ok Blood Group) (BSG) (AA 140-323) protein (Fc Tag)BSG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- CD147/Basigin
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背景
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Background: CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
Synonym: Basigin, 5F7, Collagenase Stimulatory Factor, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, Leukocyte Activation Antigen M6, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, TCSF, CD147, BSG
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分子量
- 20.7 kDa
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NCBI登录号
- NP_940991
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途径
- S100 Proteins
抗原
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