BCL6 Protein (AA 1-150) (His-TRX)
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Quick Overview for BCL6 Protein (AA 1-150) (His-TRX) (ABIN7317419)
抗原
See all BCL6 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-150
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标记
- This BCL6 protein is labelled with His-TRX.
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原理
- Recombinant Human BCL6/B-cell CLL lymphoma 6 Protein (aa 1-150, His & Trx Tag)
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序列
- Met 1-Met 150
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产品特性
- A DNA sequence encoding the human BCL6 (P41182) N-terminal fragment (Met 1-Met 150) was fused with a Trx and a polyhistidine tag at the N-terminus.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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B-Cell CLL/lymphoma 6 (BCL6) (AA 131-230) protein (GST tag)
BCL6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 6 (BCL6) (AA 1-174) protein (His-IF2DI Tag)BCL6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
B-Cell CLL/lymphoma 6 (BCL6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BCL6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 10 % glycerol, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- BCL6/B-cell CLL lymphoma 6
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背景
- BCL5;BCL6A;LAZ3;ZBTB27;ZNF51,The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.
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分子量
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Calculated MW: 34.2 kDa
Observed MW: 33 kDa
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基因ID
- 604
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UniProt
- P41182
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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