ATG3 蛋白
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北京 101111
Quick Overview for ATG3 蛋白 (ABIN7318184)
抗原
See all ATG3 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human ATG3 Protein
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序列
- Met 1-Met314
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产品特性
- Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (His tag)
ATG3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
ATG3 Autophagy Related 3 (ATG3) (AA 1-287) protein (His-IF2DI Tag)ATG3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
ATG3 Autophagy Related 3 (ATG3) (AA 1-314) protein (GST tag)ATG3 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
ATG3 Autophagy Related 3 (ATG3) (AA 1-314), (full length) protein (His-SUMO Tag)ATG3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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别名
- ATG3
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背景
- APG3,APG3-like,APG3L,ATG3,Autophagy-related protein 3,Protein PC3-96,Ubiquitin-like-conjugating enzyme ATG3,hApg3,Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98 % aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
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分子量
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Calculated MW: 36.0 kDa
Observed MW: 38 kDa
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基因ID
- 64422
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UniProt
- Q9NT62
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途径
- Autophagy
抗原
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