Arylsulfatase A Protein (ARSA) (His tag)
Quick Overview for Arylsulfatase A Protein (ARSA) (His tag) (ABIN7318179)
抗原
See all Arylsulfatase A (ARSA) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Arylsulfatase A protein is labelled with His tag.
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原理
- Recombinant Human Arylsulfatase A/ARSA Protein (His Tag)
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序列
- Arg19-Ala507
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产品特性
- Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Arylsulfatase A (ARSA)
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别名
- Arylsulfatase A/ARSA
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背景
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Background: Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.
Synonym: Arylsulfatase A, ASA, Cerebroside-Sulfatase, ARSA
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分子量
- 52.9 kDa
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UniProt
- P15289
抗原
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