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Annexin V 蛋白

This Recombinant Annexin V protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7317864
发货至: 中国

Quick Overview for Annexin V 蛋白 (ABIN7317864)

抗原

See all Annexin V (ANXA5) 蛋白
Annexin V (ANXA5) (Annexin A5 (ANXA5))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human ANXA5/Annexin V/Annexin A5 Protein

    序列

    Met 1-Asp 320

    产品特性

    A DNA sequence encoding the human ANXA5 (P08758) (Met 1-Asp 320) was expressed and purified.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile 50 mM Tris, 240 mM NaCl, pH 8.5

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Annexin V (ANXA5) (Annexin A5 (ANXA5))

    别名

    ANXA5/Annexin V/Annexin A5

    背景

    Background: Peptidyl-prolyl cis-trans isomerase A; also known as PPIase A; Rotamase A; Cyclophilin A; Cyclosporin A-binding protein; PPIA and CYPA; is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity; suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins; including p55 gag; Vpr; and capsid protein; and has been shown to be necessary for the formation of infectious HIV virions.

    Synonym: ANXA5;Annexin V;Unconjugated Annexin V;Annexin-5;Anchorin CII;Calphobindin I;Endonexin II;Lipocortin V;Placental anticoagulant protein 4;Placental anticoagulant protein I;Thromboplastin inhibitor;Vascular anticoagulant-alpha

    分子量

    35.9 kDa

    UniProt

    P08758

    途径

    Apoptosis
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