Annexin V 蛋白
Quick Overview for Annexin V 蛋白 (ABIN7317864)
抗原
See all Annexin V (ANXA5) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human ANXA5/Annexin V/Annexin A5 Protein
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序列
- Met 1-Asp 320
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产品特性
- A DNA sequence encoding the human ANXA5 (P08758) (Met 1-Asp 320) was expressed and purified.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 50 mM Tris, 240 mM NaCl, pH 8.5
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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别名
- ANXA5/Annexin V/Annexin A5
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背景
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Background: Peptidyl-prolyl cis-trans isomerase A; also known as PPIase A; Rotamase A; Cyclophilin A; Cyclosporin A-binding protein; PPIA and CYPA; is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity; suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins; including p55 gag; Vpr; and capsid protein; and has been shown to be necessary for the formation of infectious HIV virions.
Synonym: ANXA5;Annexin V;Unconjugated Annexin V;Annexin-5;Anchorin CII;Calphobindin I;Endonexin II;Lipocortin V;Placental anticoagulant protein 4;Placental anticoagulant protein I;Thromboplastin inhibitor;Vascular anticoagulant-alpha
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分子量
- 35.9 kDa
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UniProt
- P08758
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途径
- Apoptosis
抗原
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