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Angiopoietin 1 Protein (ANGPT1) (Fc Tag)

This Recombinant Angiopoietin 1 protein is expressed in 人细胞.
产品编号 ABIN7319856
发货至: 中国

Quick Overview for Angiopoietin 1 Protein (ANGPT1) (Fc Tag) (ABIN7319856)

抗原

See all Angiopoietin 1 (ANGPT1) 蛋白
Angiopoietin 1 (ANGPT1)

蛋白类型

Recombinant

宿主

  • 12
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2

资源

  • 20
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
人细胞

纯度

>95 % as determined by reducing SDS-PAGE.
  • 标记

    This Angiopoietin 1 protein is labelled with Fc Tag.

    原理

    Recombinant Human Angiopoietin-1/ANG1 (N-Fc)

    序列

    Asp256-Phe498

    产品特性

    Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Angiopoietin 1 (ANGPT1)

    别名

    Angiopoietin-1/ANG1

    背景

    Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

    Synonym: AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1

    分子量

    53.9 kDa

    UniProt

    Q15389

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process
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