Angiopoietin 1 Protein (ANGPT1) (Fc Tag)
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Quick Overview for Angiopoietin 1 Protein (ANGPT1) (Fc Tag) (ABIN7319856)
抗原
See all Angiopoietin 1 (ANGPT1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Angiopoietin 1 protein is labelled with Fc Tag.
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原理
- Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
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序列
- Asp256-Phe498
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产品特性
- Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Angiopoietin 1 (ANGPT1) (AA 20-498) protein
ANGPT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Angiopoietin 1 (ANGPT1) (AA 1-498) protein (GST tag)ANGPT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Angiopoietin 1 (ANGPT1)
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别名
- Angiopoietin-1/ANG1
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背景
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Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.
Synonym: AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1
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分子量
- 53.9 kDa
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UniProt
- Q15389
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process
抗原
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