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Interleukin 17a 蛋白

This Recombinant Interleukin 17a protein is expressed in HEK-293 Cells.
产品编号 ABIN7199556
发货至: 中国

Quick Overview for Interleukin 17a 蛋白 (ABIN7199556)

抗原

See all Interleukin 17a (IL17A) 蛋白
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.

质量等级

MALS verified
  • 原理

    Human IL-17A / CTLA-8 Protein, Tag Free (MALS verified)

    序列

    Gly 24 - Ala 155

    产品特性

    Human IL17A, Tag Free (ILA-H5219) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # Q16552-1).

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 应用备注

    This protein carries no "tag". The protein has a calculated MW of 15.1 kDa. As a result of glycosylation, the protein migrates as 16 kDa, 17 kDa and 19 kDa under reducing (R) condition, and 27-34 kDa under non-reducing (NR) condition .

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A / CTLA-8

    背景

    Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
    Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    分子量

    15.1 kDa

    NCBI登录号

    NP_002181
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