Interleukin 17a 蛋白
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Quick Overview for Interleukin 17a 蛋白 (ABIN7199556)
抗原
See all Interleukin 17a (IL17A) 蛋白蛋白类型
宿主
资源
纯度
质量等级
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原理
- Human IL-17A / CTLA-8 Protein, Tag Free (MALS verified)
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序列
- Gly 24 - Ala 155
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产品特性
- Human IL17A, Tag Free (ILA-H5219) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # Q16552-1).
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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应用备注
- This protein carries no "tag". The protein has a calculated MW of 15.1 kDa. As a result of glycosylation, the protein migrates as 16 kDa, 17 kDa and 19 kDa under reducing (R) condition, and 27-34 kDa under non-reducing (NR) condition .
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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别名
- IL-17A / CTLA-8
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背景
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Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. -
分子量
- 15.1 kDa
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NCBI登录号
- NP_002181
抗原
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