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Interleukin 17a Protein (AA 24-155) (His tag,AVI tag,Biotin)

This Recombinant Interleukin 17a protein is expressed in HEK-293 Cells.
产品编号 ABIN6810035
发货至: 中国
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Quick Overview for Interleukin 17a Protein (AA 24-155) (His tag,AVI tag,Biotin) (ABIN6810035)

抗原

See all Interleukin 17a (IL17A) 蛋白
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

蛋白类型

Recombinant

生物活性

Active

宿主

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HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.
  • 产品特性

    AA 24-155

    标记

    This Interleukin 17a protein is labelled with His tag,AVI tag,Biotin.

    序列

    AA 24-155

    特异性

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    注意事项

    Please avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A

    背景

    Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    分子量

    17.8 kDa

    NCBI登录号

    NP_002181
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