Activin RIIA / ACVR2A protein (Fc Tag)
宿主: 人
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- 抗原
- Activin RIIA / ACVR2A
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- Fc Tag
- 原理
- Human Activin RIIA / ACVR2A Protein, Fc Tag
- 序列
- Ala 20 - Pro 135
- 产品特性
- Human ACVR2A, Fc Tag (ACA-H5269) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Pro 135 (Accession # P27037-1).
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Activin RIIA / ACVR2A (Active) protein (His tag)
宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Activin RIIA / ACVR2A (Active) protein (His tag,Fc Tag)宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- 应用备注
- This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 39.9 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Activin RIIA / ACVR2A
- 背景
-
Synonyms: Activin receptor type IIA,ACTRIIA,
Description: Activin receptor type-2A (ACVR2A) is also known as Activin receptor type IIA, ACTR-IIA, ACTRIIA and ACVR2,which is single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities. - 分子量
- 39.9 kDa
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