IL17A
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
ELISA, WB
应用备注
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.
限制
仅限研究用
状态
Lyophilized
缓冲液
PBS, pH 7.4
储存条件
-20 °C
储存方法
-20°C
抗原
Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
别名
IL-17A / CTLA-8
背景
Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17, Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.