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Interleukin 17a Protein (His tag)

This Recombinant Interleukin 17a protein is expressed in HEK-293 Cells.
产品编号 ABIN7121397
发货至: 中国

Quick Overview for Interleukin 17a Protein (His tag) (ABIN7121397)

抗原

See all Interleukin 17a (IL17A) 蛋白
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.
  • 标记

    This Interleukin 17a protein is labelled with His tag.

    原理

    Canine IL-17A / CTLA-8 Protein, His Tag

    序列

    Gly 26 - Ala 155

    产品特性

    Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # C6L8D7-1).

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 应用备注

    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A / CTLA-8

    背景

    Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
    Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    分子量

    17.0 kDa

    NCBI登录号

    NM_001165878
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