CD74 Protein (Fc Tag)
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- 抗原 See all CD74 蛋白
- CD74 (HLA-DR-gamma (CD74))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD74 protein is labelled with Fc Tag.
- 原理
- Recombinant Human CD74(73-232) Protein with N-terminal human Fc tag
- 特异性
- HFc (Glu99-Ala330) CD74 (Gln73-Met232)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Discover our top product CD74 蛋白
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 146,137.28 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD74 (HLA-DR-gamma (CD74))
- 别名
- CD74 (CD74 产品)
- 背景
- The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- 分子量
- predicted molecular mass of 44.4 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD74(73-232) is 55-70 kDa due to glycosylation.
- UniProt
- P04233
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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