Sialoadhesin/CD169 Protein (AA 20-1641) (His tag)
SIGLEC1
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
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- 抗原 See all Sialoadhesin/CD169 (SIGLEC1) 蛋白
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-1641
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Sialoadhesin/CD169 protein is labelled with His tag.
- 序列
- AA 20-1641
- 产品特性
- Cynomolgus Siglec-10 Protein, His Tag
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product SIGLEC1 蛋白
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Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) protein (Myc-DYKDDDDK Tag)
SIGLEC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- MES,NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- 别名
- Siglec-1 (SIGLEC1 产品)
- 背景
- Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells.
- 分子量
- 175.1 kDa
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