Ret Proto-Oncogene Protein (RET) (Fc Tag)
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- 抗原 See all Ret Proto-Oncogene (RET) 蛋白
- Ret Proto-Oncogene (RET)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Ret Proto-Oncogene protein is labelled with Fc Tag.
- 序列
- RET (Leu29-Arg635)+hFc(GLU99-ALA330)
- 产品特性
- Tagged Protein: C-Human Fc tag
- 纯化方法
- affinity purification
- Top Product
- Discover our top product RET 蛋白
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Ret Proto-Oncogene (RET) (AA 25-458) protein (GST tag)
RET 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Ret Proto-Oncogene (RET) protein (DYKDDDDK Tag)RET 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ret Proto-Oncogene (RET) protein (DYKDDDDK-His Tag)RET 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- 有效期
- 12 months
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- 抗原
- Ret Proto-Oncogene (RET)
- 别名
- RET (RET 产品)
- 背景
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Synonymes: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
Description: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017] - 分子量
- 92.29 kDa
- UniProt
- P07949
- 途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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