CD4 Protein (CD4) (Fc Tag)
Our Local Distributor
北京 101111
Quick Overview for CD4 Protein (CD4) (Fc Tag) (ABIN6964180)
抗原
See all CD4 蛋白蛋白类型
宿主
资源
-
-
标记
- This CD4 protein is labelled with Fc Tag.
-
序列
- CD4(Lys26-Trp390)+hFc(Glu99-Ala330)
-
产品特性
- Tagged Protein: C-Human Fc tag
-
纯化方法
- affinity purification
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute with deionized water
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
储存液
- Without preservative
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
-
有效期
- 12 months
-
-
- CD4
-
别名
- CD4
-
背景
-
Synonymes: CD4,CD4mut,LEU3
Description: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. -
分子量
- 65.67 kDa
-
UniProt
- P01730
-
途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
-