SARS-CoV-2 Spike S1 Protein (Fc Tag)
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Quick Overview for SARS-CoV-2 Spike S1 Protein (Fc Tag) (ABIN6952624)
抗原
See all SARS-CoV-2 Spike S1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This SARS-CoV-2 Spike S1 protein is labelled with Fc Tag.
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原理
- SARS-CoV-2 (COVID-19) S1 protein, Fc Tag
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序列
- AA 16-685
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产品特性
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SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). Predicted N-terminus: Val 16
This protein carries a human IgG1 Fc tag at the C-terminus. -
过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Tris, Glycine and NaCl, pH 7.5
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
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For long term storage, the product should be stored at lyophilized state at -20°C or lower.
This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 years under sterile conditions after reconstitution.
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: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
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: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
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- SARS-CoV-2 Spike S1
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物质类
- Viral Protein
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背景
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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分子量
- 101.5 kDa
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基因ID
- 43740568
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UniProt
- P0DTC2
抗原
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