CCL5 Protein (AA 24-91) (Biotin)
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北京 101111
Quick Overview for CCL5 Protein (AA 24-91) (Biotin) (ABIN6952202)
抗原
See all CCL5 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 24-91
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标记
- This CCL5 protein is labelled with Biotin.
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序列
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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产品特性
- Biotininylated Recombinant Human CCL5 (Rantes)
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内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.25-0.50 nM determined by Migration Assay of recombinant CCR5 containing cells
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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储存条件
- -20 °C,-80 °C
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储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
有效期
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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别名
- CCL5 (Rantes)
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背景
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
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分子量
- 10.270 kDa
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UniProt
- P13501
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
抗原
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