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CCL5 Protein (AA 24-91) (Biotin)

This Recombinant CCL5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6952202
发货至: 中国

Quick Overview for CCL5 Protein (AA 24-91) (Biotin) (ABIN6952202)

抗原

See all CCL5 蛋白
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Cell Migration Assay (CMA)

纯度

> 97 % by SDS PAGE
  • 产品特性

    AA 24-91

    标记

    This CCL5 protein is labelled with Biotin.

    序列

    SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

    产品特性

    Biotininylated Recombinant Human CCL5 (Rantes)

    内毒素水平

    <0.01 EU per 1μg of the protein by the LAL method

    Biological Activity Comment

    EC50 = 0.25-0.50 nM determined by Migration Assay of recombinant CCR5 containing cells
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

    储存条件

    -20 °C,-80 °C

    储存方法

    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    别名

    CCL5 (Rantes)

    背景

    Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.

    分子量

    10.270 kDa

    UniProt

    P13501

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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