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CCL3 Protein (AA 24-92)

This Recombinant CCL3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6952188
发货至: 中国

Quick Overview for CCL3 Protein (AA 24-92) (ABIN6952188)

抗原

See all CCL3 蛋白
CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Cell Migration Assay (CMA)

纯度

> 97 % by SDS PAGE
  • 产品特性

    AA 24-92

    序列

    SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA

    产品特性

    Recombinant Human CCL3 (MIP-1alpha)

    内毒素水平

    <0.01 EU per 1μg of the protein by the LAL method

    Biological Activity Comment

    EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

    储存条件

    -20 °C,-80 °C

    储存方法

    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

    别名

    CCL3 (MIP-1alpha)

    背景

    Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.

    分子量

    7.716 kDa

    UniProt

    P10147

    途径

    Cellular Response to Molecule of Bacterial Origin, Autophagy
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