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CD70 Protein (AA 47-195) (His tag,AVI tag,Biotin)

This Recombinant CD70 protein is expressed in HEK-293 Cells.

SDS

Immobilized Mouse CD27, Mouse IgG2a Fc Tag, low endotoxin (ABIN5955007,ABIN6809974) at 2 μg/mL (100 μL/well) can bind Biotinylated Mouse CD27 Ligand, His,Avitag (ABIN6731315,ABIN6809905) with a linear range of 0. (CD70 Protein (AA 47-195) (His tag,AVI tag,Biotin))

ELISA

2 images

产品编号 ABIN6731315

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD70 Protein (AA 47-195) (His tag,AVI tag,Biotin) (ABIN6731315)

抗原

See all CD70 蛋白

CD70 (CD70 Molecule (CD70))

蛋白类型

Recombinant

生物活性

Active

宿主

小鼠

资源

HEK-293 Cells

纯度

>95 % as determined by SDS-PAGE.

Discover our top product CD70 蛋白

产品特性

AA 47-195

标记

This CD70 protein is labelled with His tag,AVI tag,Biotin.

序列

AA 47-195

特异性

Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

内毒素水平

Less than 1.0 EU per μg by the LAL method.
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Product

表达系统

Conjugate

Origin

价格从

CD70 Protein (AA 1-195) (His tag)

表达系统 HEK-293 Cells

Conjugate His tag

Origin Mouse

价格从 150,642.20 ¥

CD70 Protein (AA 1-195) (Strep Tag)

表达系统 Cell-free protein synthesis (CFPS)

Conjugate Strep Tag

Origin Mouse

价格从 145,985.55 ¥

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CD70 Molecule (CD70) (AA 39-193) (Active) protein (hFc Tag)
CD70 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active

CD70 Molecule (CD70) (AA 99-330) protein (His tag,mFc Tag)
CD70 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

CD70 Molecule (CD70) (AA 45-195) (Active) protein (hFc Tag)
CD70 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 50-193), (Trimer) (Active) protein (His tag)
CD70 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 50-193), (Trimer) (Active) protein (Biotin,His tag)
CD70 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

CD70 Molecule (CD70) (AA 1-195) protein (His tag)
custom-made CD70 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

CD70 Molecule (CD70) (AA 1-193) protein (His tag)
custom-made CD70 宿主: 人宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

CD70 Molecule (CD70) (AA 39-194) (Active) protein (His tag)
CD70 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active

CD70 Molecule (CD70) (AA 52-193) protein (His-DYKDDDDK-Strep II Tag)
CD70 宿主: 人宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI

CD70 Molecule (CD70) (AA 39-193) protein (His tag,Fc Tag)
CD70 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

说明

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

限制

仅限研究用
状态

Lyophilized

缓冲液

PBS, pH 7.4

注意事项

Please avoid repeated freeze-thaw cycles.

储存条件

-20 °C
抗原

CD70 (CD70 Molecule (CD70))

别名

CD27 Ligand

背景

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

分子量

20.1 kDa

途径

Cancer Immune Checkpoints