IL-15 蛋白
Quick Overview for IL-15 蛋白 (ABIN6700033)
抗原
See all IL-15 (IL15) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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Supplier Product No.
- 009-001-v53-0100
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Supplier
- Rockland
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原理
- Human Interleukin-15 Recombinant Protein
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纯化方法
- Interleukin-15 purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
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内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
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Biological Activity Comment
- The activity is determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 cells and is typcially less than 0.5 ng/mL.
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应用备注
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Application Note: Interleukin-15 Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-15 in immunological assays. Lyophilized in 10 mM sodium bicarbonate, pH 8.5.
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
- Lyophilized in 10 mM sodium bicarbonate, pH 8.5.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
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有效期
- 6 months
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- IL-15 (IL15) (Interleukin 15 (IL15))
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别名
- IL15
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背景
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Synonyms: IL-T
Background: Interleukin 15 (IL-15) is a widely expressed pro-inflammatory cytokine related to IL-2. IL-15 promotes activation of T cells, neutrophils and macrophages and is critical to dendritic cell function in several model systems. IL-15 has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases. Emerging data suggests that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells. Recombinant human IL-15 is a non-glycosylated protein, containing 114 amino acids, with a molecular weight of 12.8 kDa.
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UniProt
- P40933
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途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
抗原
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