Quick Overview for FKBP3 Protein (AA 1-224) (ABIN666953)
抗原
See all FKBP3 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 1-224
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序列
- MAAAVPQRAW TVEQLRSEQL PKKDIIKFLQ EHGSDSFLAE HKLLGNIKNV AKTANKDHLV TAYNHLFETK RFKGTESISK VSEQVKNVKL NEDKPKETKS EETLDEGPPK YTKSVLKKGD KTNFPKKGDV VHCWYTGTLQ DGTVFDTNIQ TSAKKKKNAK PLSFKVGVGK VIRGWDEALL TMSKGEKARL EIEPEWAYGK KGQPDAKIPP NAKLTFEVEL VDID
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产品特性
- FKBP3, 1-224aa, Human, E.coli
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纯化方法
- > 90% by SDS-PAGE
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Biological Activity Comment
- Specific activity is > 900nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
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FK506 Binding Protein 3, 25kDa (FKBP3) (AA 1-224) protein (GST tag)
FKBP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 3, 25kDa (FKBP3) (AA 1-224) (Active) proteinFKBP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS Active
FK506 Binding Protein 3, 25kDa (FKBP3) (AA 2-224) protein (His-SUMO Tag)FKBP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
FK506 Binding Protein 3, 25kDa (FKBP3) protein (Myc-DYKDDDDK Tag)FKBP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
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别名
- FKBP25/FKBP3
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背景
- FK506 binding protein 3 (FKBP3), also known as FKBP25, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. Also, FKBP3 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation. It is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. Recombinant human FKBP3 was expressed in E. coli and purified by using conventional chromatography techniques.
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分子量
- 25.1 kDa (224aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_002004
抗原
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