FKBP3 Protein (AA 1-224) (His tag)
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- 抗原 See all FKBP3 蛋白
- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-224
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This FKBP3 protein is labelled with His tag.
- 原理
- Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP3 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MAAAVPQRAW TVEQLRSEQL PKKDIIKFLQ EHGSDSFLAE HKLLGNIKNV AKTANKDHLV TAYNHLFETK RFKGTESISK VSEQVKNVKL NEDKPKETKS EETLDEGPPK YTKSVLKKGD KTNFPKKGDV VHCWYTGTLQ DGTVFDTNIQ TSAKKKKNAK PLSFKVGVGK VIRGWDEALL TMSKGEKARL EIEPEWAYGK KGQPDAKIPP NAKLTFEVEL VDID
- 产品特性
- Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp224) of Human FKBP3/FKBP25 fused with a 6His tag at the N-terminus..
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FKBP3 蛋白
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FK506 Binding Protein 3, 25kDa (FKBP3) (AA 1-224) protein
FKBP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
FK506 Binding Protein 3, 25kDa (FKBP3) (AA 1-224) protein (GST tag)FKBP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 3, 25kDa (FKBP3) (AA 2-224) protein (His-SUMO Tag)FKBP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
FK506 Binding Protein 3, 25kDa (FKBP3) protein (Myc-DYKDDDDK Tag)FKBP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mM DTT,10 % glycerol .
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
- 别名
- Peptidyl-Prolyl Cis-Trans Isomerase FKBP3 (FKBP3 产品)
- 别名
- FKBP3 Protein, 25kDa Protein, FKBP-3 Protein, FKBP25 Protein, FK506 Protein, fb75c04 Protein, si:dz261o22.2 Protein, wu:fb75c04 Protein, zgc:110728 Protein, FKBP-25 Protein, PPIase Protein, FK506 binding protein 3 Protein, FK506 binding protein 3 L homeolog Protein, peptidylprolyl isomerase Protein, FKBP3 Protein, Fkbp3 Protein, fkbp3 Protein, fkbp3.L Protein, CAALFM_C103790CA Protein
- 背景
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FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP3,PPIase FKBP3,25 kDa FK506-binding protein,25 kDa FKBP,FKBP-25,FK506-binding protein 3,FKBP-3,Immunophilin FKBP25,Rapamycin-selective 25 kDa immunophilin,Rotamase,FKBP25 - 分子量
- 27.3 kDa
- UniProt
- Q00688
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