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Quick Overview for SKP1 Protein (AA 1-160) (ABIN666914)
抗原
See all SKP1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-160
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序列
- MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL
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产品特性
- SKP1, 1- 160aa, Human, E.coli
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纯化方法
- > 90% by SDS-PAGE
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S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) protein (GST tag)
SKP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) proteinSKP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
S-Phase Kinase-Associated Protein 1 (SKP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SKP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
S-Phase Kinase-Associated Protein 1 (SKP1) (AA 2-163) protein (GST tag)SKP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 50 mM NaCl, 10 % glycerol
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注意事项
- Avoid repeated freezing and thawing cycles
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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别名
- SKP1
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背景
- S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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分子量
- 18 kDa (160aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_008861
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
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