Liquid in 20mM Tris pH 8.0, 1mM EDTA, 0.5mM DTT, 10% glycerol.
储存条件
4 °C
抗原
HMGB1
(High Mobility Group Box 1 (HMGB1))
别名
HMGB1
背景
High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor. Recombinant human HMGB1 was expressed in High Five insect cells and purified by conventional chromatography techniques. Synonyms: HMG1, HMG3, SBP-1, High-mobility group box1, HMGB1, High-mobility group box1, high-mobility group (nonhistone chromosomal) protein 1, Sulfoglucuronyl carbohydrate binding protein, Amphoterin, high mobility group protein 1, DKFZp686A04236. NCBI no.: NP_002119