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IL-4 Protein (AA 25-153)

This Recombinant IL-4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6387871
发货至: 中国

Quick Overview for IL-4 Protein (AA 25-153) (ABIN6387871)

抗原

See all IL-4 (IL4) 蛋白
IL-4 (IL4) (Interleukin 4 (IL4))

蛋白类型

Recombinant

生物活性

Active

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS), Activity Assay (AcA)

纯度

> 95% by SDS-PAGE
  • 产品特性

    AA 25-153

    序列

    MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Bioactivity Validated

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL-4

    背景

    IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.

    分子量

    15 kDa (130aa)

    NCBI登录号

    NP_000580

    UniProt

    P05112

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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