IL-4 Protein (AA 25-153)
-
- 抗原 See all IL-4 (IL4) 蛋白
- IL-4 (IL4) (Interleukin 4 (IL4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-153
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS), Activity Assay (AcA)
- 序列
- MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
- 纯度
- > 95% by SDS-PAGE
- 内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6ng/ml.
- Top Product
- Discover our top product IL4 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
Bioactivity Validated
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- IL-4 (IL4) (Interleukin 4 (IL4))
- 别名
- IL-4 (IL4 产品)
- 背景
- IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.
- 分子量
- 15 kDa (130aa)
- NCBI登录号
- NP_000580
- UniProt
- P05112
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
-