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IL-4 Protein (AA 25-153)

IL4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
产品编号 ABIN6387871
发货至: 中国
  • 抗原 See all IL-4 (IL4) 蛋白
    IL-4 (IL4) (Interleukin 4 (IL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 25-153
    宿主
    • 38
    • 26
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    资源
    • 53
    • 20
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    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS), Activity Assay (AcA)
    序列
    MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
    纯度
    > 95% by SDS-PAGE
    内毒素水平
    < 1 EU per 1ug of protein (determined by LAL method)
    Biological Activity Comment
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6ng/ml.
    Top Product
    Discover our top product IL4 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Bioactivity Validated

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原
    IL-4 (IL4) (Interleukin 4 (IL4))
    别名
    IL-4 (IL4 产品)
    背景
    IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.
    分子量
    15 kDa (130aa)
    NCBI登录号
    NP_000580
    UniProt
    P05112
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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