FLT1 Protein (AA 23-759) (Fc Tag)
Quick Overview for FLT1 Protein (AA 23-759) (Fc Tag) (ABIN6253654)
抗原
See all FLT1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 23-759
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标记
- This FLT1 protein is labelled with Fc Tag.
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序列
- AA 23-759
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产品特性
- This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 109.8 kDa. The protein migrates as 140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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内毒素水平
- Less than 0.1 EU per μg by the LAL method.
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Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) protein (His-Avi Tag)
FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) protein (His-Avi Tag,Biotin)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (glycosylated), (Monomer), (Soluble) (Active) proteinFLT1 宿主: 人 宿主: Insect Cells Recombinant > 90 % by SDS-PAGE Active
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) protein (His tag)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) protein (Fc Tag)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) (Active) protein (His tag,AVI tag,Biotin)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (Active) protein (His tag)FLT1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 581-687) protein (GST tag)FLT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- VEGF R1
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背景
- Vascular endothelial growth factor receptor 1 (VEGFR1) is also known as Fms-like tyrosine kinase 1 (FLT-1), Tyrosine-protein kinase receptor FLT, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR1 is detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues and specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR1 acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR1 may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. VEGFR1 can promote endothelial cell proliferation, survival and angiogenesis in adulthood.
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分子量
- 109.8 kDa
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NCBI登录号
- NP_034358
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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