FGF2 蛋白
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北京 101111
Quick Overview for FGF2 蛋白 (ABIN623547)
抗原
See all FGF2 蛋白蛋白类型
宿主
宿主
纯度
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序列
- The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Ala-Gly-Ser.
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产品特性
- Recombinant Bovine Fibroblast Growth Factor-basic
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过滤
- Sterile
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 0.85 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program
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缓冲液
- The FGF-b Bovine was lyophilized from a concentrated (1mg/ml) sterile solution containing 1%HSA.It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-2 Bovine Recombinant in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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储存条件
- -20 °C
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- Fibroblast Growth Factor-Basic
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背景
- FGF-2 Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17250 Dalton. The Fibroblast Growth Factor 2 is purified by proprietary chromatographic techniques. Introduction: FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. there are differences in the tissue distribution and concentration of these 2 growth factors. Synonyms: HBGH-2, HBGF-2, Prostatropin, FGF-2, FGB-b.
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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