FGF2 蛋白
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北京 101111
Quick Overview for FGF2 蛋白 (ABIN624488)
抗原
See all FGF2 蛋白蛋白类型
宿主
宿主
纯度
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序列
- The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Glu-Gly-Glu-Ile
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产品特性
- Recombinant Human Fibroblast Growth Factor-basic
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 0.8511 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis progra
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缓冲液
- The protein was lyophilized from a concentrated (1mg/ml) solution in PBS, pH 7.4.It is recommended to reconstitute the lyophilized Fibroblast Growth Factor Basic in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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储存条件
- -20 °C
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: "The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage." in: Scientific reports, Vol. 5, pp. 10412, (2015) (PubMed).
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- Fibroblast Growth Factor-Basic
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背景
- Fibroblast Growth Factor-2 Human Recombinant (FGF-2) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17353 Dalton. The FGF-b is purified by proprietary chromatographic techniques. Introduction: Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. Synonyms: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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