FOLR1 Protein (AA 25-233) (His tag,AVI tag,Biotin)
Quick Overview for FOLR1 Protein (AA 25-233) (His tag,AVI tag,Biotin) (ABIN5954995)
抗原
See all FOLR1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 25-233
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标记
- This FOLR1 protein is labelled with His tag,AVI tag,Biotin.
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序列
- AA 25-233
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特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His-Avi Tag)
FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-234) protein (His tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (Fc Tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His-Avi Tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-232) protein (His tag)FOLR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (Fc Tag,AVI tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 1-257) protein (GST tag)FOLR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. -
限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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别名
- FOLR1
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背景
- Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
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分子量
- 28.3 kDa
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NCBI登录号
- NP_057937
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途径
- Dicarboxylic Acid Transport
抗原
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