Caspase 3 Protein (CASP3) (AA 176-277)
This Recombinant Caspase 3 protein is expressed in 大肠杆菌（E. Coli）.
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Quick Overview for Caspase 3 Protein (CASP3) (AA 176-277) (ABIN7280651)
抗原
See all Caspase 3 (CASP3) 蛋白
Caspase 3 (CASP3)
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
SDS-PAGE (SDS)
纯度
> 80% by SDS-PAGE
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产品特性
- AA 176-277
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序列
- MSGVDDDMAC HKIPVEADFL YAYSTAPGYY SWRNSKDGSW FIQSLCAMLK QYADKLEFMH ILTRVNRKVA TEFESFSFDA TFHAKKQIPC IVSMLTKELY FYH
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Caspase 3 (CASP3) (AA 29-277) protein (His-IF2DI Tag)
CASP3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Caspase 3 (CASP3) (AA 1-277) protein (GST tag)CASP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Denatured
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Caspase 3 (CASP3)
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别名
- Caspase-3
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背景
- CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Recombinant human CASP3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
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分子量
- 12 kDa (103aa)
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NCBI登录号
- NP_116786
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UniProt
- P42574
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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