RAB11A Protein (AA 2-213) (His-SUMO Tag)
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- 抗原 See all RAB11A 蛋白
- RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-213
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This RAB11A protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- GTRDDEYDYL FKVVLIGDSG VGKSNLLSRF TRNEFNLESK STIGVEFATR SIQVDGKTIK AQIWDTAGQE RYRAITSAYY RGAVGALLVY DIAKHLTYEN VERWLKELRD HADSNIVIML VGNKSDLRHL RAVPTDEARA FAEKNGLSFI ETSALDSTNV EAAFQTILTE IYRIVSQKQM SDRRENDMSP SNNVVPIHVP PTTENKPKVQ CC
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product RAB11A 蛋白
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RAB11A, Member RAS Oncogene Family (RAB11A) (AA 1-213) protein (His tag)
RAB11A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
RAB11A, Member RAS Oncogene Family (RAB11A) (AA 1-216) protein (GST tag)RAB11A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
RAB11A, Member RAS Oncogene Family (RAB11A) protein (Myc-DYKDDDDK Tag)RAB11A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
- 别名
- RB11A (RAB11A 产品)
- 背景
- The small GTPases Rab are key regulators of intracellular mbrane trafficking, from the formation of transport vesicles to their fusion with mbranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to mbranes different set of downstream effectors directly responsible for vesicle formation, movent, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of mbrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical mbrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma mbrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma mbrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma mbrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral mbranes. May also play a role in melanosome transport and release from melanocytes.
- 分子量
- 39.89 kDa
- UniProt
- P62491
- 途径
- Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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