PSME3 Protein (PSME3) (partial) (His tag)
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北京 101111
Quick Overview for PSME3 Protein (PSME3) (partial) (His tag) (ABIN5608460)
抗原
See all PSME3 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial
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标记
- This PSME3 protein is labelled with His tag.
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序列
- Met 1 - Tyr 254
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内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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应用备注
- This recombinant protein can be used for WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 200 mM NaCl, pH 8.0
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- PSME3
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别名
- PSME3
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背景
- Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.
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分子量
- 30.3 kDa
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基因ID
- 10197
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NCBI登录号
- NP_00578
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UniProt
- P61289
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
抗原
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