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PSME3 Protein (PSME3) (partial) (His tag)

This Recombinant PSME3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN5608460
发货至: 中国

Quick Overview for PSME3 Protein (PSME3) (partial) (His tag) (ABIN5608460)

抗原

See all PSME3 蛋白
PSME3

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Western Blotting (WB)

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    partial

    标记

    This PSME3 protein is labelled with His tag.

    序列

    Met 1 - Tyr 254

    内毒素水平

    Endotoxin level is less than 1.0 EU per ug by the LAL method.
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  • 应用备注

    This recombinant protein can be used for WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    50 mM Tris, 200 mM NaCl, pH 8.0

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C,-80 °C

    储存方法

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原

    PSME3

    别名

    PSME3

    背景

    Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.

    分子量

    30.3 kDa

    基因ID

    10197

    NCBI登录号

    NP_00578

    UniProt

    P61289

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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