PD-L1 Protein (partial) (Fc Tag)
Quick Overview for PD-L1 Protein (partial) (Fc Tag) (ABIN5608343)
抗原
See all PD-L1 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
产品特性
- partial
-
标记
- This PD-L1 protein is labelled with Fc Tag.
-
序列
- Phe 19 - Thr 238
-
内毒素水平
- Endotoxin level is less than 0.1 EU per ug by the LAL method.
-
-
-
-
应用备注
- This recombinant protein can be used for WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- PBS, pH 7.4
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
-
-
- PD-L1 (CD274 (PD-L1))
-
别名
- PD-L1
-
背景
- Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
-
分子量
- 51.8 kDa
-
基因ID
- 60533
-
UniProt
- Q9EP73
-
途径
- Cancer Immune Checkpoints
抗原
-