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PD-L1 Protein (partial) (Fc Tag)

This Recombinant PD-L1 protein is expressed in HEK-293 Cells.
产品编号 ABIN5608343
发货至: 中国

Quick Overview for PD-L1 Protein (partial) (Fc Tag) (ABIN5608343)

抗原

See all PD-L1 蛋白
PD-L1 (CD274 (PD-L1))

蛋白类型

Recombinant

宿主

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小鼠

资源

  • 49
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HEK-293 Cells

应用范围

Western Blotting (WB)

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    partial

    标记

    This PD-L1 protein is labelled with Fc Tag.

    序列

    Phe 19 - Thr 238

    内毒素水平

    Endotoxin level is less than 0.1 EU per ug by the LAL method.
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  • 应用备注

    This recombinant protein can be used for WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C,-80 °C

    储存方法

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    PD-L1

    背景

    Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

    分子量

    51.8 kDa

    基因ID

    60533

    UniProt

    Q9EP73

    途径

    Cancer Immune Checkpoints
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