S100A8 Protein (partial)
Quick Overview for S100A8 Protein (partial) (ABIN5608247)
抗原
See all S100A8 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial
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序列
- Met 1 - Glu 93
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内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- This recombinant protein can be used for WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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别名
- S100A8
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背景
- S100 calcium binding protein A8 (S100-A8) is also kown as Cystic fibrosis antigen, Migration inhibitory factor-related protein 8 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF and P8, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S100A9. S100A8 and S100A9 are known to be overexpressed in certain species of carcinomas. S100A8 may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. S100A8 plays an important role in differentiation of thyroid carcinoma possibly by forming a complex with S100A9. S100A8 and S100A9 may also play a key role in inflammation-associated cancer.
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分子量
- 10.8 kDa
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基因ID
- 6279
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NCBI登录号
- NP_002955
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UniProt
- P05109
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途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
抗原
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