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S100A8 Protein (partial)

This Recombinant S100A8 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN5608247
发货至: 中国

Quick Overview for S100A8 Protein (partial) (ABIN5608247)

抗原

See all S100A8 蛋白
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

蛋白类型

Recombinant

宿主

  • 13
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资源

  • 22
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大肠杆菌(E. Coli)

应用范围

Western Blotting (WB)

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    partial

    序列

    Met 1 - Glu 93

    内毒素水平

    Endotoxin level is less than 1.0 EU per ug by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 106,314.67 ¥

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  • 应用备注

    This recombinant protein can be used for WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C,-80 °C

    储存方法

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S100A8

    背景

    S100 calcium binding protein A8 (S100-A8) is also kown as Cystic fibrosis antigen, Migration inhibitory factor-related protein 8 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF and P8, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S100A9. S100A8 and S100A9 are known to be overexpressed in certain species of carcinomas. S100A8 may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. S100A8 plays an important role in differentiation of thyroid carcinoma possibly by forming a complex with S100A9. S100A8 and S100A9 may also play a key role in inflammation-associated cancer.

    分子量

    10.8 kDa

    基因ID

    6279

    NCBI登录号

    NP_002955

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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