CD28 Protein (CD28) (partial) (His tag)
Quick Overview for CD28 Protein (CD28) (partial) (His tag) (ABIN5608228)
抗原
See all CD28 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial
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标记
- This CD28 protein is labelled with His tag.
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序列
- Asn 20 - Lys 149
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内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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应用备注
- This recombinant protein can be used for WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- CD28
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别名
- CD28
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背景
- T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
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分子量
- 17 kDa
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基因ID
- 12487
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NCBI登录号
- NP_031668
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UniProt
- P31041
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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