Betacellulin Protein (BTC) (partial) (Fc Tag)
Quick Overview for Betacellulin Protein (BTC) (partial) (Fc Tag) (ABIN5608199)
抗原
See all Betacellulin (BTC) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial
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标记
- This Betacellulin protein is labelled with Fc Tag.
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序列
- Asp 32 - Tyr 111
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内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (Fc Tag)BTC 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- This recombinant protein can be used for WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Betacellulin (BTC)
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别名
- Betacellulin
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背景
- Probetacellulin can be cleaved into the Betacellulin (BTC) that is a single-pass type I membrane protein containing 1 EGF-like domain. Predominantly expressed in pancreas and small intestine,Betacellulin (BTC) is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. As a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells, Betacellulin (BTC) is also the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Betacellulin (BTC) was originally identified as a growth-promoting factor in mouse pancreatic beta-cell carcinoma cell line and has since been identified in humans. The amino acid sequence of mature mBTC is 82.5 % , identical with that of human BTC (hBTC), and both exhibit significant overall similarity with other members of the EGF family.
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分子量
- 36.5 kDa
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基因ID
- 685
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UniProt
- P35070
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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