CD86 Protein (CD86) (DYKDDDDK-His Tag)
Quick Overview for CD86 Protein (CD86) (DYKDDDDK-His Tag) (ABIN5505589)
抗原
See all CD86 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This CD86 protein is labelled with DYKDDDDK-His Tag.
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产品特性
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- Recombinant human Purified recombinant protein of human CD86 Molecule (CD86), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
- Produced with end-sequenced ORF clone
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纯化方法
- Purified
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 1 x PBS, pH 7.4, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD86
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别名
- CD86 molecule
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背景
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
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分子量
- 27 kDa
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NCBI登录号
- NP_787058
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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