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CD86 Protein (CD86) (DYKDDDDK-His Tag)

This Recombinant CD86 protein is expressed in HEK-293 Cells.
产品编号 ABIN5505589
发货至: 中国
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Quick Overview for CD86 Protein (CD86) (DYKDDDDK-His Tag) (ABIN5505589)

抗原

See all CD86 蛋白
CD86

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This CD86 protein is labelled with DYKDDDDK-His Tag.

    产品特性

    • Recombinant human Purified recombinant protein of human CD86 Molecule (CD86), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
    • Produced with end-sequenced ORF clone

    纯化方法

    Purified
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    1 x PBS, pH 7.4, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    CD86

    别名

    CD86 molecule

    背景

    This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

    分子量

    27 kDa

    NCBI登录号

    NP_787058

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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