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CD276 Protein (CD276) (DYKDDDDK-His Tag)

This Recombinant CD276 protein is expressed in HEK-293 Cells.
产品编号 ABIN5505582
发货至: 中国

Quick Overview for CD276 Protein (CD276) (DYKDDDDK-His Tag) (ABIN5505582)

抗原

See all CD276 蛋白
CD276

蛋白类型

Recombinant

宿主

  • 29
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资源

  • 29
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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This CD276 protein is labelled with DYKDDDDK-His Tag.

    产品特性

    • Recombinant human Purified recombinant protein of human CD276 Molecule (CD276), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
    • Produced with end-sequenced ORF clone

    纯化方法

    Purified
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    1 x PBS, pH 7.4, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    CD276

    别名

    CD276 molecule

    背景

    The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    49 kDa

    NCBI登录号

    NP_001019907

    途径

    Cancer Immune Checkpoints
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