Caspase 2 蛋白
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- 抗原 See all Caspase 2 (CASP2) 蛋白
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 产品特性
- ~10,000 units/mg. One unit cleaves 1nmole of the caspase substrate VDVAD-pNA per hour at 37°C in a reaction solution containing 50mM HEPES, pH 7.2, 50mM NaCl, 0.1% CHAPS, 10mM EDTA, 5% glycerol and 10mM DTT.
- Top Product
- Discover our top product CASP2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with PBS to 1 unit/µl.
- 储存条件
- -80 °C
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- 抗原
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- 别名
- Caspase-2 (CASP2 产品)
- 别名
- xCaspase-2 Protein, Caspase-2 Protein, ICH-1 Protein, Nedd2 Protein, CASP-2 Protein, ICH1 Protein, NEDD-2 Protein, NEDD2 Protein, PPP1R57 Protein, ICH-1L/1S Protein, ICH1L1S Protein, caspase 2 Protein, caspase 2 L homeolog Protein, caspase-2 Protein, CASP2 Protein, casp2.L Protein, CpipJ_CPIJ008254 Protein, Casp2 Protein
- 背景
- Caspase-2 (also known as Ich-1, Nedd-2) is a member of the interleukin-1 converting enzyme (ICE) family of cysteine proteases. Similar as other caspases, caspase-2 also exists in cells as an inactive proenzyme. During apoptosis, procaspase-2 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases. The processed form of caspase-2 consists of large (19 kDa) and small (12 kDa) subunits, which associate to form the active enzyme. The active recombinant human caspase-2 was expressed in E. coli. The expressed caspase-2 spontaneously undergoes auto-processing to yield the subunits characteristic of the native enzyme.
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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